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Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Teneurins are ancient cell–cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event when a bacterial YD-repeat toxin fused to a eukaryotic receptor. We present X-ray crystallography and...

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Detalles Bibliográficos
Autores principales: Jackson, Verity A., Meijer, Dimphna H., Carrasquero, Maria, van Bezouwen, Laura S., Lowe, Edward D., Kleanthous, Colin, Janssen, Bert J. C., Seiradake, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851990/
https://www.ncbi.nlm.nih.gov/pubmed/29540701
http://dx.doi.org/10.1038/s41467-018-03460-0