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Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
Teneurins are ancient cell–cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event when a bacterial YD-repeat toxin fused to a eukaryotic receptor. We present X-ray crystallography and...
Autores principales: | Jackson, Verity A., Meijer, Dimphna H., Carrasquero, Maria, van Bezouwen, Laura S., Lowe, Edward D., Kleanthous, Colin, Janssen, Bert J. C., Seiradake, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851990/ https://www.ncbi.nlm.nih.gov/pubmed/29540701 http://dx.doi.org/10.1038/s41467-018-03460-0 |
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