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Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme

The assembly of membranous extensions such as microvilli and cilia in polarized cells is a tightly regulated, yet poorly understood, process. Peptidylglycine α-amidating monooxygenase (PAM), a membrane enzyme essential for the synthesis of amidated bioactive peptides, was recently identified in moti...

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Detalles Bibliográficos
Autores principales: Kumar, Dhivya, Thomason, Rebecca T., Yankova, Maya, Gitlin, Jonathan D., Mains, Richard E., Eipper, Betty A., King, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852006/
https://www.ncbi.nlm.nih.gov/pubmed/29540787
http://dx.doi.org/10.1038/s41598-018-22732-9