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Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme
The assembly of membranous extensions such as microvilli and cilia in polarized cells is a tightly regulated, yet poorly understood, process. Peptidylglycine α-amidating monooxygenase (PAM), a membrane enzyme essential for the synthesis of amidated bioactive peptides, was recently identified in moti...
Autores principales: | Kumar, Dhivya, Thomason, Rebecca T., Yankova, Maya, Gitlin, Jonathan D., Mains, Richard E., Eipper, Betty A., King, Stephen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852006/ https://www.ncbi.nlm.nih.gov/pubmed/29540787 http://dx.doi.org/10.1038/s41598-018-22732-9 |
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