Compression force sensing regulates integrin α(IIb)β(3) adhesive function on diabetic platelets

Diabetes is associated with an exaggerated platelet thrombotic response at sites of vascular injury. Biomechanical forces regulate platelet activation, although the impact of diabetes on this process remains ill-defined. Using a biomembrane force probe (BFP), we demonstrate that compressive force ac...

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Detalles Bibliográficos
Autores principales: Ju, Lining, McFadyen, James D., Al-Daher, Saheb, Alwis, Imala, Chen, Yunfeng, Tønnesen, Lotte L., Maiocchi, Sophie, Coulter, Brianna, Calkin, Anna C., Felner, Eric I., Cohen, Neale, Yuan, Yuping, Schoenwaelder, Simone M., Cooper, Mark E., Zhu, Cheng, Jackson, Shaun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852038/
https://www.ncbi.nlm.nih.gov/pubmed/29540687
http://dx.doi.org/10.1038/s41467-018-03430-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852038/
https://www.ncbi.nlm.nih.gov/pubmed/29540687
http://dx.doi.org/10.1038/s41467-018-03430-6

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