Cargando…

Dopamine D1 receptor density in the mPFC responds to cognitive demands and receptor turnover contributes to general cognitive ability in mice

In both humans and mice, performance on tests of intelligence or general cognitive ability (GCA) is related to dopamine D1 receptor-mediated activity in the prelimbic cortex, and levels of DRD1 mRNA predict the GCA of mice. Here we assessed the turnover rate of D1 receptors as well as the expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wass, Christopher, Sauce, Bruno, Pizzo, Alessandro, Matzel, Louis D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852043/ https://www.ncbi.nlm.nih.gov/pubmed/29540721 http://dx.doi.org/10.1038/s41598-018-22668-0

Ejemplares similares

Dopamine D1 sensitivity in the prefrontal cortex predicts general cognitive abilities and is modulated by working memory training
por: Wass, Christopher, et al.
Publicado: (2013)

Dopamine-induced astrocytic Ca(2+) signaling in mPFC is mediated by MAO-B in young mice, but by dopamine receptors in adult mice
por: Kim, Sunpil, et al.
Publicado: (2022)

Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
por: Klune, Cassandra B, et al.
Publicado: (2021)

Dysfunction of the NAc-mPFC circuit in insomnia disorder
por: Shao, Ziqiang, et al.
Publicado: (2020)

AAV-Mediated Overexpression of the CB1 Receptor in the mPFC of Adult Rats Alters Cognitive Flexibility, Social Behavior, and Emotional Reactivity
por: Klugmann, Matthias, et al.
Publicado: (2011)

Chemogenetic activation of the HPC-mPFC pathway improves cognitive dysfunction in lipopolysaccharide -induced brain injury
por: Ge, Chenglong, et al.
Publicado: (2023)

The Neurotrophic Receptor Tyrosine Kinase in MEC-mPFC Neurons Contributes to Remote Memory Consolidation
por: Hong, Jongryul, et al.
Publicado: (2022)

Amygdala GABA Neurons Project To vlPAG And mPFC
por: Sun, Ying, et al.
Publicado: (2019)

Nucleus Accumbens Shell and mPFC but Not Insula Orexin-1 Receptors Promote Excessive Alcohol Drinking
por: Lei, Kelly, et al.
Publicado: (2016)

Positive modulation of N-methyl-D-aspartate receptors in the mPFC reduces the spontaneous recovery of fear
por: Lee, Boyoung, et al.
Publicado: (2022)

Neuroplastic Correlates in the mPFC Underlying the Impairment of Stress-Coping Ability and Cognitive Flexibility in Adult Rats Exposed to Chronic Mild Stress during Adolescence
por: Zhang, Yu, et al.
Publicado: (2017)

Spontaneous synchronous network activity in the neonatal development of mPFC in mice
por: Pires, Johny, et al.
Publicado: (2021)

HMGB1 in the mPFC governs comorbid anxiety in neuropathic pain
por: Du, Yu, et al.
Publicado: (2022)

Social Behavior Is Modulated by Valence-Encoding mPFC-Amygdala Sub-circuitry
por: Huang, Wen-Chin, et al.
Publicado: (2020)

The role of mPFC and MTL neurons in human choice under goal-conflict
por: Gazit, Tomer, et al.
Publicado: (2020)

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
por: Fogaça, Manoela V., et al.
Publicado: (2020)

Neural Representation in mPFC Reveals Hidden Selfish Motivation in White Lies
por: Kim, JuYoung, et al.
Publicado: (2021)

Effects of Chronic Dopamine D2R Agonist Treatment and Polysialic Acid Depletion on Dendritic Spine Density and Excitatory Neurotransmission in the mPFC of Adult Rats
por: Castillo-Gómez, Esther, et al.
Publicado: (2016)

5-HT2a receptor in mPFC influences context-guided reconsolidation of object memory in perirhinal cortex
por: Morici, Juan Facundo, et al.
Publicado: (2018)

Involvement of Oxytocin Receptor/Erk/MAPK Signaling in the mPFC in Early Life Stress-Induced Autistic-Like Behaviors
por: Wei, Jinbao, et al.
Publicado: (2020)

Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence
por: Xu, Hang, et al.
Publicado: (2016)

Optogenetic Stimulation of mPFC Alleviates White Matter Injury‐Related Cognitive Decline after Chronic Ischemia through Adaptive Myelination
por: Deng, Shiji, et al.
Publicado: (2022)

NPY Receptor 2 Mediates NPY Antidepressant Effect in the mPFC of LPS Rat by Suppressing NLRP3 Signaling Pathway
por: Wang, Wenjiao, et al.
Publicado: (2019)

Uncertainty-Dependent Extinction of Fear Memory in an Amygdala-mPFC Neural Circuit Model
por: Li, Yuzhe, et al.
Publicado: (2016)

A multi-faceted role of dual-state dopamine signaling in working memory, attentional control, and intelligence
por: Matzel, Louis D., et al.
Publicado: (2023)

Synergistic, long-term effects of glutamate dehydrogenase 1 deficiency and mild stress on cognitive function and mPFC gene and miRNA expression
por: Asraf, Kfir, et al.
Publicado: (2023)

Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice
por: Wang, Lun, et al.
Publicado: (2023)

Author Correction: The role of mPFC and MTL neurons in human choice under goal-conflict
por: Gazit, Tomer, et al.
Publicado: (2020)

Natural sleep loss is associated with lower mPFC activity during negative distracter processing
por: Dimitrov, Annika, et al.
Publicado: (2021)

Effect of intracerebroventricular injection of GABA receptors antagonists on morphine-induced changes in GABA and GLU transmission within the mPFC: an in vivo microdialysis study
por: Ramshini, Effat, et al.
Publicado: (2019)

Extracellular Nucleosomes Accelerate Microglial Inflammation via C-Type Lectin Receptor 2D and Toll-Like Receptor 9 in mPFC of Mice With Chronic Stress
por: Wu, Huanghui, et al.
Publicado: (2022)

Effect of Physical Activity on Symptoms of Morphine Addiction in Rats, after and before of Lesion of the mPFC Area
por: Saedi Marghmaleki, Vajiheh, et al.
Publicado: (2013)

Optogenetic stimulation of mPFC pyramidal neurons as a conditioned stimulus supports associative learning in rats
por: Wu, Guang-yan, et al.
Publicado: (2015)

Subregional differences in the generation of fast network oscillations in the rat medial prefrontal cortex (mPFC) in vitro
por: Glykos, Vasileios, et al.
Publicado: (2015)

Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep–Wake EEG Disturbances
por: Lou, Tingting, et al.
Publicado: (2020)

Activation of dopaminergic VTA inputs to the mPFC ameliorates chronic stress‐induced breast tumor progression
por: Xu, Xi‐Rong, et al.
Publicado: (2020)

Insula to mPFC reciprocal connectivity differentially underlies novel taste neophobic response and learning in mice
por: Kayyal, Haneen, et al.
Publicado: (2021)

Decreased phase information transfer from the mPFC to the BLA: During exploratory behavior in CUMS rats
por: Cao, Qingying, et al.
Publicado: (2023)

Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory
por: Wu, Jing, et al.
Publicado: (2023)

Multiple routes of communication within the amygdala-mPFC network: A comparative approach in humans and macaques
por: Giacometti, C., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_a877mik1l4st3897lu804r2ja7