Many Routes to an Antibody Heavy-Chain CDR3: Necessary, Yet Insufficient, for Specific Binding

Because of its great potential for diversity, the immunoglobulin heavy-chain complementarity-determining region 3 (HCDR3) is taken as an antibody molecule’s most important component in conferring binding activity and specificity. For this reason, HCDR3s have been used as unique identifiers to invest...

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Detalles Bibliográficos
Autores principales: D’Angelo, Sara, Ferrara, Fortunato, Naranjo, Leslie, Erasmus, M. Frank, Hraber, Peter, Bradbury, Andrew R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852061/
https://www.ncbi.nlm.nih.gov/pubmed/29568296
http://dx.doi.org/10.3389/fimmu.2018.00395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852061/
https://www.ncbi.nlm.nih.gov/pubmed/29568296
http://dx.doi.org/10.3389/fimmu.2018.00395

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