Four TRPM4 Cation Channel Mutations Found in Cardiac Conduction Diseases Lead to Altered Protein Stability

Transient receptor potential melastatin member 4 (TRPM4), a non-selective cation channel, mediates cell membrane depolarization in immune response, insulin secretion, neurological disorders, and cancer. Pathological variants in TRPM4 gene have been linked to several cardiac phenotypes such as comple...

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Detalles Bibliográficos
Autores principales: Bianchi, Beatrice, Ozhathil, Lijo Cherian, Medeiros-Domingo, Argelia, Gollob, Michael H., Abriel, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852105/
https://www.ncbi.nlm.nih.gov/pubmed/29568272
http://dx.doi.org/10.3389/fphys.2018.00177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852105/
https://www.ncbi.nlm.nih.gov/pubmed/29568272
http://dx.doi.org/10.3389/fphys.2018.00177

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