Synthesis, antimicrobial activity, pharmacophore modeling and molecular docking studies of new pyrazole-dimedone hybrid architectures

BACKGROUND: Design and synthesis of pyrazole-dimedone derivatives were described by one-pot multicomponent reaction as new antimicrobial agents. These new molecular framework were synthesized in high yields with a broad substrate scope under benign conditions mediated by diethylamine (NHEt(2)). The...

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Detalles Bibliográficos
Autores principales: Barakat, Assem, Al-Majid, Abdullah M., Al-Qahtany, Bander M., Ali, M., Teleb, Mohamed, Al-Agamy, Mohamed H., Naz, Sehrish, Ul-Haq, Zaheer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852137/
https://www.ncbi.nlm.nih.gov/pubmed/29541952
http://dx.doi.org/10.1186/s13065-018-0399-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852137/
https://www.ncbi.nlm.nih.gov/pubmed/29541952
http://dx.doi.org/10.1186/s13065-018-0399-0

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