Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity

During mammalian heart development, restricted myocardial Bmp2 expression is a key patterning signal for atrioventricular canal specification and the epithelial–mesenchyme transition that gives rise to the valves. Using a mouse transgenic line conditionally expressing Bmp2, we show that widespread B...

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Detalles Bibliográficos
Autores principales: Prados, Belén, Gómez-Apiñániz, Paula, Papoutsi, Tania, Luxán, Guillermo, Zaffran, Stephane, Pérez-Pomares, José María, de la Pompa, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852166/
https://www.ncbi.nlm.nih.gov/pubmed/29540665
http://dx.doi.org/10.1038/s41419-018-0442-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852166/
https://www.ncbi.nlm.nih.gov/pubmed/29540665
http://dx.doi.org/10.1038/s41419-018-0442-z

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