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Myocardial Bmp2 gain causes ectopic EMT and promotes cardiomyocyte proliferation and immaturity
During mammalian heart development, restricted myocardial Bmp2 expression is a key patterning signal for atrioventricular canal specification and the epithelial–mesenchyme transition that gives rise to the valves. Using a mouse transgenic line conditionally expressing Bmp2, we show that widespread B...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852166/ https://www.ncbi.nlm.nih.gov/pubmed/29540665 http://dx.doi.org/10.1038/s41419-018-0442-z |