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Structure and function of the Nppa–Nppb cluster locus during heart development and disease

Atrial natriuretic factor and brain natriuretic peptide are two important biomarkers in clinical cardiology. These two natriuretic peptide hormones are encoded by the paralogous genes Nppa and Nppb, which are evolutionary conserved. Both genes are predominantly expressed by the heart muscle during t...

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Detalles Bibliográficos
Autores principales: Man, Joyce, Barnett, Phil, Christoffels, Vincent M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852170/
https://www.ncbi.nlm.nih.gov/pubmed/29302701
http://dx.doi.org/10.1007/s00018-017-2737-0