Application of a Genetic Risk Score to Racially Diverse Type 1 Diabetes Populations Demonstrates the Need for Diversity in Risk-Modeling

Prior studies identified HLA class-II and 57 additional loci as contributors to genetic susceptibility for type 1 diabetes (T1D). We hypothesized that race and/or ethnicity would be contextually important for evaluating genetic risk markers previously identified from Caucasian/European cohorts. We d...

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Detalles Bibliográficos
Autores principales: Perry, Daniel J., Wasserfall, Clive H., Oram, Richard A., Williams, MacKenzie D., Posgai, Amanda, Muir, Andrew B., Haller, Michael J., Schatz, Desmond A., Wallet, Mark A., Mathews, Clayton E., Atkinson, Mark A., Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852207/
https://www.ncbi.nlm.nih.gov/pubmed/29540798
http://dx.doi.org/10.1038/s41598-018-22574-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852207/
https://www.ncbi.nlm.nih.gov/pubmed/29540798
http://dx.doi.org/10.1038/s41598-018-22574-5

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