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Prebiotic attenuation of olanzapine-induced weight gain in rats: analysis of central and peripheral biomarkers and gut microbiota

Olanzapine is an effective antipsychotic drug but since it causes significant weight gain, it is not well tolerated by psychosis patients. The prebiotic, B-GOS(®), attenuates metabolic dysfunction in obese subjects, and in rodents, alters central NMDA receptors and may affect serotonin receptors tha...

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Detalles Bibliográficos
Autores principales: Kao, Amy Chia-Ching, Spitzer, Sonia, Anthony, Daniel C., Lennox, Belinda, Burnet, Philip W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852210/
https://www.ncbi.nlm.nih.gov/pubmed/29540664
http://dx.doi.org/10.1038/s41398-018-0116-8