Loss of ezrin expression reduced the susceptibility to the glomerular injury in mice

Ezrin is highly expressed in glomerular podocytes and is reported to form a multi-protein complex with scaffold protein Na(+)/H(+) exchanger regulatory factor 2 (NHERF2) and podocalyxin, a major sialoprotein. Podocalyxin-knockout mice died within 24 h of birth with anuric renal failure, whereas NHER...

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Detalles Bibliográficos
Autores principales: Hatano, Ryo, Takeda, Ai, Abe, Yukiko, Kawaguchi, Kotoku, Kazama, Itsuro, Matsubara, Mitsunobu, Asano, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852236/
https://www.ncbi.nlm.nih.gov/pubmed/29540766
http://dx.doi.org/10.1038/s41598-018-22846-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852236/
https://www.ncbi.nlm.nih.gov/pubmed/29540766
http://dx.doi.org/10.1038/s41598-018-22846-0

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