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Loss of ezrin expression reduced the susceptibility to the glomerular injury in mice
Ezrin is highly expressed in glomerular podocytes and is reported to form a multi-protein complex with scaffold protein Na(+)/H(+) exchanger regulatory factor 2 (NHERF2) and podocalyxin, a major sialoprotein. Podocalyxin-knockout mice died within 24 h of birth with anuric renal failure, whereas NHER...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852236/ https://www.ncbi.nlm.nih.gov/pubmed/29540766 http://dx.doi.org/10.1038/s41598-018-22846-0 |