The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes

BACKGROUND & AIMS: Aberrations in the esophageal proliferation-differentiation gradient are histologic hallmarks in eosinophilic esophagitis (EoE) and gastroesophageal reflux disease. A reliable protocol to grow 3-dimensional (3D) esophageal organoids is needed to study esophageal epithelial hom...

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Detalles Bibliográficos
Autores principales: Kasagi, Yuta, Chandramouleeswaran, Prasanna M., Whelan, Kelly A., Tanaka, Koji, Giroux, Veronique, Sharma, Medha, Wang, Joshua, Benitez, Alain J., DeMarshall, Maureen, Tobias, John W., Hamilton, Kathryn E., Falk, Gary W., Spergel, Jonathan M., Klein-Szanto, Andres J., Rustgi, Anil K., Muir, Amanda B., Nakagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852293/
https://www.ncbi.nlm.nih.gov/pubmed/29552622
http://dx.doi.org/10.1016/j.jcmgh.2017.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852293/
https://www.ncbi.nlm.nih.gov/pubmed/29552622
http://dx.doi.org/10.1016/j.jcmgh.2017.12.013

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