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Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain

Huntington’s disease (HD) is an intractable neurodegenerative disorder caused by mutant Huntingtin (HTT) proteins that adversely affect various biomolecules and genes. MicroRNAs (miRNAs), which are functional small non-coding RNAs, are also affected by mutant HTT proteins. Here, we show amelioration...

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Detalles Bibliográficos
Autores principales: Fukuoka, Masashi, Takahashi, Masaki, Fujita, Hiromi, Chiyo, Tomoko, Popiel, H. Akiko, Watanabe, Shoko, Furuya, Hirokazu, Murata, Miho, Wada, Keiji, Okada, Takashi, Nagai, Yoshitaka, Hohjoh, Hirohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852323/
https://www.ncbi.nlm.nih.gov/pubmed/29858092
http://dx.doi.org/10.1016/j.omtn.2018.01.007