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A review of somatic single nucleotide variant calling algorithms for next-generation sequencing data

Detection of somatic mutations holds great potential in cancer treatment and has been a very active research field in the past few years, especially since the breakthrough of the next-generation sequencing technology. A collection of variant calling pipelines have been developed with different under...

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Detalles Bibliográficos
Autor principal: Xu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852328/
https://www.ncbi.nlm.nih.gov/pubmed/29552334
http://dx.doi.org/10.1016/j.csbj.2018.01.003