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PRMT5 promotes cell proliferation by inhibiting BTG2 expression via the ERK signaling pathway in hepatocellular carcinoma

Increasing evidence suggests that PRMT5, a protein arginine methyltransferase, has roles in cell growth regulation and cancer development. However, the role of PRMT5 in hepatocellular carcinoma (HCC) progression remains unclear. Here, we showed that PRMT5 expression was frequently upregulated in HCC...

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Detalles Bibliográficos
Autores principales: Jiang, Hai, Zhu, Yue, Zhou, Zhenyu, Xu, Junyang, Jin, Shaowen, Xu, Kang, Zhang, Heyun, Sun, Qing, Wang, Jie, Xu, Junyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852340/
https://www.ncbi.nlm.nih.gov/pubmed/29441724
http://dx.doi.org/10.1002/cam4.1360