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Diverse and Abundant Secondary Metabolism Biosynthetic Gene Clusters in the Genomes of Marine Sponge Derived Streptomyces spp. Isolates

The genus Streptomyces produces secondary metabolic compounds that are rich in biological activity. Many of these compounds are genetically encoded by large secondary metabolism biosynthetic gene clusters (smBGCs) such as polyketide synthases (PKS) and non-ribosomal peptide synthetases (NRPS) which...

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Detalles Bibliográficos
Autores principales: Jackson, Stephen A., Crossman, Lisa, Almeida, Eduardo L., Margassery, Lekha Menon, Kennedy, Jonathan, Dobson, Alan D.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852495/
https://www.ncbi.nlm.nih.gov/pubmed/29461500
http://dx.doi.org/10.3390/md16020067