Lactomycins A–C, Dephosphorylated Phoslactomycin Derivatives That Inhibit Cathepsin B, from the Marine-Derived Streptomyces sp. ACT232

Three new polyketides, lactomycins A (1)–C (3), were isolated from the culture broth of a marine-derived Streptomyces sp. ACT232 as cathepsin B inhibitors. Their structures were determined by a combination of NMR and MS data analyses to be the dephosphorylated derivatives of a phoslactomycin class o...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Carandang, Rogie Royce, Harada, Yuta, Okada, Shigeru, Yoshitake, Kazutoshi, Asakawa, Shuichi, Nogi, Yuichi, Matsunaga, Shigeki, Takada, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852498/
https://www.ncbi.nlm.nih.gov/pubmed/29466301
http://dx.doi.org/10.3390/md16020070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852498/
https://www.ncbi.nlm.nih.gov/pubmed/29466301
http://dx.doi.org/10.3390/md16020070

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