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Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling
OBJECTIVE: Atherosclerosis is a focal disease occurring at arterial sites of disturbed blood flow that generates low oscillating shear stress. Endothelial inflammatory signalling is enhanced at sites of disturbed flow via mechanisms that are incompletely understood. The influence of disturbed flow o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852506/ https://www.ncbi.nlm.nih.gov/pubmed/29126223 http://dx.doi.org/10.1093/cvr/cvx213 |