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Atheroprone flow activates inflammation via endothelial ATP-dependent P2X7-p38 signalling

OBJECTIVE: Atherosclerosis is a focal disease occurring at arterial sites of disturbed blood flow that generates low oscillating shear stress. Endothelial inflammatory signalling is enhanced at sites of disturbed flow via mechanisms that are incompletely understood. The influence of disturbed flow o...

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Detalles Bibliográficos
Autores principales: Green, Jack P, Souilhol, Celine, Xanthis, Ioannis, Martinez-Campesino, Laura, Bowden, Neil P, Evans, Paul C, Wilson, Heather L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852506/
https://www.ncbi.nlm.nih.gov/pubmed/29126223
http://dx.doi.org/10.1093/cvr/cvx213