Regional acidosis locally inhibits but remotely stimulates Ca(2+) waves in ventricular myocytes

AIMS: Spontaneous Ca(2+) waves in cardiomyocytes are potentially arrhythmogenic. A powerful controller of Ca(2+) waves is the cytoplasmic H(+) concentration ([H(+)](i)), which fluctuates spatially and temporally in conditions such as myocardial ischaemia/reperfusion. H(+)-control of Ca(2+) waves is...

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Detalles Bibliográficos
Autores principales: Ford, Kerrie L., Moorhouse, Emma L., Bortolozzi, Mario, Richards, Mark A., Swietach, Pawel, Vaughan-Jones, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852542/
https://www.ncbi.nlm.nih.gov/pubmed/28339694
http://dx.doi.org/10.1093/cvr/cvx033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852542/
https://www.ncbi.nlm.nih.gov/pubmed/28339694
http://dx.doi.org/10.1093/cvr/cvx033

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