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Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signalling and cross-talk with TGFβ

AIMS: Vascular calcification is a major cause of morbidity and mortality. Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown. Therefore, we investigated the involvement of FGF-2 in vascular calcificati...

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Detalles Bibliográficos
Autores principales: Borland, Samantha J., Morris, Thomas G., Borland, Shona C., Morgan, Mark R., Francis, Sheila E., Merry, Catherine L.R., Canfield, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852548/
https://www.ncbi.nlm.nih.gov/pubmed/29016732
http://dx.doi.org/10.1093/cvr/cvx178