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Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signalling and cross-talk with TGFβ
AIMS: Vascular calcification is a major cause of morbidity and mortality. Fibroblast growth factor-2 (FGF-2) plays an instructive role in osteogenesis and bone development, but its role in vascular calcification was unknown. Therefore, we investigated the involvement of FGF-2 in vascular calcificati...
Autores principales: | Borland, Samantha J., Morris, Thomas G., Borland, Shona C., Morgan, Mark R., Francis, Sheila E., Merry, Catherine L.R., Canfield, Ann E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852548/ https://www.ncbi.nlm.nih.gov/pubmed/29016732 http://dx.doi.org/10.1093/cvr/cvx178 |
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