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RhoB: Team Oncogene or Team Tumor Suppressor?

Although Rho GTPases RhoA, RhoB, and RhoC share more than 85% amino acid sequence identity, they play very distinct roles in tumor progression. RhoA and RhoC have been suggested in many studies to contribute positively to tumor development, but the role of RhoB in cancer remains elusive. RhoB contai...

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Detalles Bibliográficos
Autores principales: Ju, Julia A., Gilkes, Daniele M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852563/
https://www.ncbi.nlm.nih.gov/pubmed/29385717
http://dx.doi.org/10.3390/genes9020067