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Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates

Oligonucleotide-based therapy has become an alternative to classical approaches in the search of novel therapeutics involving gene-related diseases. Several mechanisms have been described in which demonstrate the pivotal role of oligonucleotide for modulating gene expression. Antisense oligonucleoti...

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Detalles Bibliográficos
Autores principales: Grijalvo, Santiago, Alagia, Adele, Jorge, Andreia F., Eritja, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852570/
https://www.ncbi.nlm.nih.gov/pubmed/29415514
http://dx.doi.org/10.3390/genes9020074