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MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1

Interleukin-13 (IL-13) is an important Type 2 T helper (Th2) cytokine, controlling biological functions in epithelium and has been linked to asthma, atopic dermatitis and ulcerative colitis (UC). Interleukin-13 signals through IL-13 receptor α-1 (IL13RA1 (gene) and IL13Rα1 (protein)), a receptor tha...

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Detalles Bibliográficos
Autores principales: Gwiggner, Markus, Martinez-Nunez, Rocio T., Whiteoak, Simon R., Bondanese, Victor P., Claridge, Andy, Collins, Jane E., Cummings, J. R. Fraser, Sanchez-Elsner, Tilman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852581/
https://www.ncbi.nlm.nih.gov/pubmed/29438285
http://dx.doi.org/10.3390/genes9020085