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Functional interleukin‐6 receptor‐α is located in tanycytes at the base of the third ventricle

Interleukin (IL)‐6(−)/(−) mice develop mature onset obesity, whereas i.c.v. injection of IL‐6 decreases obesity in rodents. Moreover, levels of IL‐6 in cerebrospinal fluid (CSF) were reported to be inversely correlated with obesity in humans. Tanycytes lining the base of the third ventricle (3V) in...

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Detalles Bibliográficos
Autores principales: Anesten, F., Santos, C., Gidestrand, E., Schéle, E., Pálsdóttir, V., Swedung‐Wettervik, T., Meister, B., Patrycja Skibicka, K., Jansson, J.‐O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852644/
https://www.ncbi.nlm.nih.gov/pubmed/29024103
http://dx.doi.org/10.1111/jne.12546