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Interaction between SNCA, LRRK2 and GAK increases susceptibility to Parkinson's disease in a Chinese population

PD is a complex disease, and may result from gene–gene and gene–environment interactions. There are limited studies on gene–gene interactions in PD. We and others have previously shown that SNCA rs356219, LRRK2 (rs2046932 and rs7304279) and GAK (rs1564282) are risk factors in sporadic PD. Since the...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Juan, Cheng, Lan, Li, Nan-Nan, Wang, Ling, Tan, Eng-King, Peng, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852682/
https://www.ncbi.nlm.nih.gov/pubmed/29479569
http://dx.doi.org/10.1016/j.ensci.2015.08.001