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The Dynamic Effects of Isosteviol on Insulin Secretion and Its Inability to Counteract the Impaired β-Cell Function during Gluco-, Lipo-, and Aminoacidotoxicity: Studies In Vitro

Isosteviol (ISV), a diterpene molecule, is an isomer of the backbone structure of a group of substances with proven antidiabetic capabilities. The aim of this study was to investigate if ISV elicits dynamic insulin release from pancreatic islets and concomitantly is able to ameliorate gluco-, lipo-,...

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Detalles Bibliográficos
Autores principales: Gu, Wenqian, Rebsdorf, Andreas, Hermansen, Kjeld, Gregersen, Søren, Jeppesen, Per Bendix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852703/
https://www.ncbi.nlm.nih.gov/pubmed/29373526
http://dx.doi.org/10.3390/nu10020127