PPARγ Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling

BACKGROUND AND AIMS: Accumulating evidence reveals that PPARγ plays a unique role in the regulation of hepatic fibrosis and hepatic stellate cells (HSCs) activation. This study was aimed at investigating the role of PPARγ in hypoxia-induced hepatic fibrogenesis and its possible mechanism. METHODS: R...

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Detalles Bibliográficos
Autores principales: Zhang, Qinghui, Xiang, Shihao, Liu, Qingqian, Gu, Tao, Yao, Yongliang, Lu, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852857/
https://www.ncbi.nlm.nih.gov/pubmed/29686697
http://dx.doi.org/10.1155/2018/6970407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852857/
https://www.ncbi.nlm.nih.gov/pubmed/29686697
http://dx.doi.org/10.1155/2018/6970407

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