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Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?

BACKGROUND: Exosomes isolated from plasma of patients with sepsis may induce vascular apoptosis and myocardial dysfunction by mechanisms related to inflammation and oxidative stress. Despite previous studies demonstrating that these vesicles contain genetic material related to cellular communication...

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Detalles Bibliográficos
Autores principales: Real, Juliana Monte, Ferreira, Ludmila Rodrigues Pinto, Esteves, Gustavo Henrique, Koyama, Fernanda Christtanini, Dias, Marcos Vinícius Salles, Bezerra-Neto, João Evangelista, Cunha-Neto, Edécio, Machado, Flavia Ribeiro, Salomão, Reinaldo, Azevedo, Luciano Cesar Pontes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852953/
https://www.ncbi.nlm.nih.gov/pubmed/29540208
http://dx.doi.org/10.1186/s13054-018-2003-3