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SUMOylation modulates FOXK2-mediated paclitaxel sensitivity in breast cancer cells

The forkhead transcription factor FOXK2 plays a critical role in suppressing tumorigenesis and mediating cytotoxic drug action in breast cancer. However, the mechanism by which the biological function of FOXK2 is regulated remains poorly understood. Here, we investigated the role of SUMOylation in m...

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Detalles Bibliográficos
Autores principales: Nestal de Moraes, Gabriela, Ji, Zongling, Fan, Lavender Y.-N., Yao, Shang, Zona, Stefania, Sharrocks, Andrew D., Lam, Eric W.-F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852961/
https://www.ncbi.nlm.nih.gov/pubmed/29540677
http://dx.doi.org/10.1038/s41389-018-0038-6