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SUMOylation modulates FOXK2-mediated paclitaxel sensitivity in breast cancer cells
The forkhead transcription factor FOXK2 plays a critical role in suppressing tumorigenesis and mediating cytotoxic drug action in breast cancer. However, the mechanism by which the biological function of FOXK2 is regulated remains poorly understood. Here, we investigated the role of SUMOylation in m...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852961/ https://www.ncbi.nlm.nih.gov/pubmed/29540677 http://dx.doi.org/10.1038/s41389-018-0038-6 |