Cargando…
SUMOylation modulates FOXK2-mediated paclitaxel sensitivity in breast cancer cells
The forkhead transcription factor FOXK2 plays a critical role in suppressing tumorigenesis and mediating cytotoxic drug action in breast cancer. However, the mechanism by which the biological function of FOXK2 is regulated remains poorly understood. Here, we investigated the role of SUMOylation in m...
Autores principales: | Nestal de Moraes, Gabriela, Ji, Zongling, Fan, Lavender Y.-N., Yao, Shang, Zona, Stefania, Sharrocks, Andrew D., Lam, Eric W.-F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852961/ https://www.ncbi.nlm.nih.gov/pubmed/29540677 http://dx.doi.org/10.1038/s41389-018-0038-6 |
Ejemplares similares
-
FOXK2 Transcription Factor and Its Emerging Roles in Cancer
por: Nestal de Moraes, Gabriela, et al.
Publicado: (2019) -
Functional interactions between the Forkhead transcription factor FOXK1 and the MADS-box protein SRF
por: Freddie, Cecilie T., et al.
Publicado: (2007) -
Cell Cycle-dependent Regulation of the Forkhead Transcription Factor FOXK2 by CDK·Cyclin Complexes
por: Marais, Anett, et al.
Publicado: (2010) -
The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation
por: Ji, Zongling, et al.
Publicado: (2021) -
Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer
por: de Moraes, G Nestal, et al.
Publicado: (2015)