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Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells

BACKGROUND: Fibrinogen is a central player in the blood coagulation cascade and one of the most abundant plasma proteins. This glycoprotein also triggers important events (e.g., cell spreading, the respiratory burst and degranulation) in neutrophil cells via a α(M)β(2) integrin-mediated binding to t...

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Detalles Bibliográficos
Autores principales: Alberio, Tiziana, Forlani, Greta, Lualdi, Marta, Tosi, Giovanna, Accolla, Roberto S., Fasano, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853075/
https://www.ncbi.nlm.nih.gov/pubmed/29540212
http://dx.doi.org/10.1186/s12967-018-1446-2