Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate

BACKGROUND: Extracellular vesicles (EVs) are important in the intercellular communication of the central nervous system, and their release is increased during neuroinflammation. Our previous data demonstrated an increased release of EVs during HIV-1 infection and immune activation in glial cells. Ho...

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Detalles Bibliográficos
Autores principales: Wu, Beiqing, Liu, Jianhui, Zhao, Runze, Li, Yuju, Peer, Justin, Braun, Alexander L., Zhao, Lixia, Wang, Yi, Tong, Zenghan, Huang, Yunlong, Zheng, Jialin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853116/
https://www.ncbi.nlm.nih.gov/pubmed/29540215
http://dx.doi.org/10.1186/s12974-018-1120-x