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A Zebrafish Model of Mycobacterium leprae Granulomatous Infection

Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in the ectothermic zebrafish. We found that nonc...

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Detalles Bibliográficos
Autores principales: Madigan, Cressida A, Cameron, James, Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853370/
https://www.ncbi.nlm.nih.gov/pubmed/28934421
http://dx.doi.org/10.1093/infdis/jix329