HBV-Derived Synthetic Long Peptide Can Boost CD4(+) and CD8(+) T-Cell Responses in Chronic HBV Patients Ex Vivo

BACKGROUND: Vaccination with synthetic long peptides (SLP) is a promising new treatment strategy for chronic hepatitis B virus (CHB). SLP can induce broad T-cell responses for all HLA types. Here we investigated the ability of a prototype HBV-core (HBc)-sequence-derived SLP to boost HBV-specific T c...

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Detalles Bibliográficos
Autores principales: Dou, Yingying, van Montfoort, Nadine, van den Bosch, Aniek, de Man, Robert A, Zom, Gijs G, Krebber, Willem-Jan, Melief, Cornelis J M, Buschow, Sonja I, Woltman, Andrea M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853453/
https://www.ncbi.nlm.nih.gov/pubmed/29220492
http://dx.doi.org/10.1093/infdis/jix614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853453/
https://www.ncbi.nlm.nih.gov/pubmed/29220492
http://dx.doi.org/10.1093/infdis/jix614

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