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An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus

Biosynthesis of many ecologically important secondary metabolites (SMs) in filamentous fungi is controlled by several global transcriptional regulators, like the chromatin modifier LaeA, and tied to both development and vegetative growth. In Aspergillus molds, asexual development is regulated by the...

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Detalles Bibliográficos
Autores principales: Lind, Abigail L., Lim, Fang Yun, Soukup, Alexandra A., Keller, Nancy P., Rokas, Antonis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853485/
https://www.ncbi.nlm.nih.gov/pubmed/29564395
http://dx.doi.org/10.1128/mSphere.00050-18