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Systematic Bias Introduced by Genomic DNA Template Dilution in 16S rRNA Gene-Targeted Microbiota Profiling in Human Stool Homogenates

Variability in representation of microbial communities can be caused by differences in microbial composition or artifacts introduced at sample collection or processing. Alterations in community representation introduced by variations in starting DNA concentrations have not been systematically invest...

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Detalles Bibliográficos
Autores principales: Multinu, Francesco, Harrington, Sean C., Chen, Jun, Jeraldo, Patricio R., Johnson, Stephen, Chia, Nicholas, Walther-Antonio, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853488/
https://www.ncbi.nlm.nih.gov/pubmed/29564398
http://dx.doi.org/10.1128/mSphere.00560-17