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Mimicking the cardiac cycle in intact cardiomyocytes using diastolic and systolic force clamps; measuring power output

AIMS: A single isolated cardiomyocyte is the smallest functional unit of the heart. Yet, all single isolated cardiomyocyte experiments have been limited by the lack of proper methods that could reproduce a physiological cardiac cycle. We aimed to investigate the contractile properties of a single ca...

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Detalles Bibliográficos
Autores principales: Helmes, Michiel, Najafi, Aref, Palmer, Bradley M., Breel, Ernst, Rijnveld, Niek, Iannuzzi, Davide, van der Velden, Jolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853507/
https://www.ncbi.nlm.nih.gov/pubmed/27037258
http://dx.doi.org/10.1093/cvr/cvw072