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Fetal Metabolic Stress Disrupts Immune Homeostasis and Induces Proinflammatory Responses in Human Immunodeficiency Virus Type 1– and Combination Antiretroviral Therapy–Exposed Infants

Increased morbidity and fetal growth restriction are reported in uninfected children born to human immunodeficiency virus type 1 (HIV-1)–infected women treated with antiretroviral (ARV) therapy. Viruses and/or pharmacological interventions such as ARVs can induce metabolic stress, skewing the cell’s...

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Detalles Bibliográficos
Autores principales: Schoeman, Johannes C, Moutloatse, Gontse P, Harms, Amy C, Vreeken, Rob J, Scherpbier, Henriette J, Van Leeuwen, Liesbeth, Kuijpers, Taco W, Reinecke, Carools J, Berger, Ruud, Hankemeier, Thomas, Bunders, Madeleine J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853663/
https://www.ncbi.nlm.nih.gov/pubmed/28633455
http://dx.doi.org/10.1093/infdis/jix291