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Dysregulated T-Helper Type 1 (Th1):Th2 Cytokine Profile and Poor Immune Response in Pregnant Ferrets Infected With 2009 Pandemic Influenza A(H1N1) Virus

Pregnancy has been associated with severe influenza, an association highlighted during the 2009 pandemic of influenza A(H1N1) virus (A[H1N1]pdm09) infection. To assess the underlying mechanism, we infected pregnant and non-pregnant ferrets with A(H1N1) pdm09 virus. A(H1N1)pdm09-infected pregnant fer...

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Detalles Bibliográficos
Autores principales: Yoon, Sun-Woo, Wong, Sook-San, Zhu, Huachen, Chen, Rirong, Li, Long, Zhang, Yu, Guan, Yi, Webby, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853788/
https://www.ncbi.nlm.nih.gov/pubmed/28973317
http://dx.doi.org/10.1093/infdis/jix328