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An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance

Unveiling the detailed roles of glutathione (GSH) in chemoresistance necessitates a reliable assay for its detection in intact live specimens. Herein, by taking advantage of the susceptibility of electron-poor C(sp(2))–S(sufinyl) bond to GSH nucleophilic attack, we developed a naphthalimide–sulfoxid...

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Detalles Bibliográficos
Autores principales: Jiang, Yuejing, Cheng, Juan, Yang, Chengyu, Hu, Yongzhou, Li, Jia, Han, Yifeng, Zang, Yi, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853925/
https://www.ncbi.nlm.nih.gov/pubmed/29568448
http://dx.doi.org/10.1039/c7sc03338a