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An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance
Unveiling the detailed roles of glutathione (GSH) in chemoresistance necessitates a reliable assay for its detection in intact live specimens. Herein, by taking advantage of the susceptibility of electron-poor C(sp(2))–S(sufinyl) bond to GSH nucleophilic attack, we developed a naphthalimide–sulfoxid...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853925/ https://www.ncbi.nlm.nih.gov/pubmed/29568448 http://dx.doi.org/10.1039/c7sc03338a |