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Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites

Heterochromatin-dependent gene silencing is central to the adaptation and survival of Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during blood infection in humans. By assessing genome-wide heterochromatin protein 1 (HP1) occupancy, we present a comprehensive an...

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Detalles Bibliográficos
Autores principales: Fraschka, Sabine A., Filarsky, Michael, Hoo, Regina, Niederwieser, Igor, Yam, Xue Yan, Brancucci, Nicolas M.B., Mohring, Franziska, Mushunje, Annals T., Huang, Ximei, Christensen, Peter R., Nosten, Francois, Bozdech, Zbynek, Russell, Bruce, Moon, Robert W., Marti, Matthias, Preiser, Peter R., Bártfai, Richárd, Voss, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853956/
https://www.ncbi.nlm.nih.gov/pubmed/29503181
http://dx.doi.org/10.1016/j.chom.2018.01.008