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Comparative Heterochromatin Profiling Reveals Conserved and Unique Epigenome Signatures Linked to Adaptation and Development of Malaria Parasites
Heterochromatin-dependent gene silencing is central to the adaptation and survival of Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during blood infection in humans. By assessing genome-wide heterochromatin protein 1 (HP1) occupancy, we present a comprehensive an...
Autores principales: | Fraschka, Sabine A., Filarsky, Michael, Hoo, Regina, Niederwieser, Igor, Yam, Xue Yan, Brancucci, Nicolas M.B., Mohring, Franziska, Mushunje, Annals T., Huang, Ximei, Christensen, Peter R., Nosten, Francois, Bozdech, Zbynek, Russell, Bruce, Moon, Robert W., Marti, Matthias, Preiser, Peter R., Bártfai, Richárd, Voss, Till S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853956/ https://www.ncbi.nlm.nih.gov/pubmed/29503181 http://dx.doi.org/10.1016/j.chom.2018.01.008 |
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