A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial

OBJECTIVES: Randomized controlled trials (RCTs) deliver robust internally valid evidence but generalizability is often neglected. Design features built into the Prostate testing for cancer and Treatment (ProtecT) RCT of treatments for localized prostate cancer (PCa) provided insights into its genera...

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Detalles Bibliográficos
Autores principales: Donovan, Jenny L., Young, Grace J., Walsh, Eleanor I., Metcalfe, Chris, Lane, J. Athene, Martin, Richard M., Tazewell, Marta K., Davis, Michael, Peters, Tim J., Turner, Emma L., Mills, Nicola, Khazragui, Hanan, Khera, Tarnjit K., Neal, David E., Hamdy, Freddie C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854278/
https://www.ncbi.nlm.nih.gov/pubmed/29288137
http://dx.doi.org/10.1016/j.jclinepi.2017.12.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854278/
https://www.ncbi.nlm.nih.gov/pubmed/29288137
http://dx.doi.org/10.1016/j.jclinepi.2017.12.019

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