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Physiological oxygen culture reveals retention of metabolic memory in human induced pluripotent stem cells

Reprogramming somatic cells to a pluripotent cell state (induced Pluripotent Stem (iPS) cells) requires reprogramming of metabolism to support cell proliferation and pluripotency, most notably changes in carbohydrate turnover that reflect a shift from oxidative to glycolytic metabolism. Some aspects...

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Detalles Bibliográficos
Autores principales: Harvey, Alexandra J., O’Brien, Carmel, Lambshead, Jack, Sheedy, John R., Rathjen, Joy, Laslett, Andrew L., Gardner, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854358/
https://www.ncbi.nlm.nih.gov/pubmed/29543848
http://dx.doi.org/10.1371/journal.pone.0193949